Usually, the ADF input file is a shell script, that has the ending .run and contains all instructions to perform the simulation with ADF (you can find an example for such an input file below in the example section). You can submit your ADF job with the following command:
bsub [LSF options] < my_ADF_input_file.run
Here you need to replace [LSF options] with LSF parameters for the resource requirements of the job. Please find a documentation about the parameters of bsub on the wiki page about the batch system.