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You can submit a SAMtools job in batch mode with the following command:

bsub [LSF options] "samtools [samtools options]"

Here you need to replace [samtools options] with SAMtools command line options (please run the command samtools for getting a list of all command line options) and [LSF options] with LSF parameters for the resource requirements of the job. Please find a documentation about the parameters of bsub on the wiki page about the batch system.